Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
C360A | 2% of wild-type activity | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-diethyl-2-hydroxy-2-nitroso-hydrazine | nitric oxide donor, inhibition via S-nitrosylation of Cys360 in the active site of ODC | Rattus norvegicus | |
S-nitrosoglutathione | inhibition likely via S-transnitrosation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | Rattus norvegicus | first step in polyamine biosynthesis | putrescine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinnt ODC | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | - |
Rattus norvegicus | putrescine + CO2 | - |
? | |
L-ornithine | first step in polyamine biosynthesis | Rattus norvegicus | putrescine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ODC | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |