Literature summary for 4.1.1.17 extracted from

Moyano, N.; Frydman, J.; Buldain, G.; Ruiz, O.; Frydman, R.B.
Inhibition of ornithine decarboxylase by the isomers of 1,4-dimethylputrescine (1990), J. Med. Chem., 33, 1969-1974.

Inhibitors

Inhibitors	Comment	Organism	Structure
1,4-Dimethylputrescine	none of the three isomers, meso, +, and - inhibits in vitro, but strongly inhibits in vivo in rats or in H-35 hepatoma cells	Rattus norvegicus

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-Orn	-	Rattus norvegicus	Putrescine + CO2	-	?

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Release 2023.1 (January 2023)