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Literature summary for 4.1.1.17 extracted from
- Characterization of a high affinity membrane-associated ornithine decarboxylase from the free-living nematode Caenorhabditis elegans (1990), Biochem. J., 270, 599-604.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| agmatine | non-competitive | Caenorhabditis elegans |  |
| alpha-DL-difluoromethylornithine | - |
Caenorhabditis elegans | |
| DL-alpha-Monofluoromethylornithine | - |
Caenorhabditis elegans | |
| EDTA | - |
Caenorhabditis elegans | |
| L-Arg | - |
Caenorhabditis elegans | |
| Lys | - |
Caenorhabditis elegans | |
| putrescine | - |
Caenorhabditis elegans | |
| spermidine | noncompetitive | Caenorhabditis elegans | |
| spermine | noncompetitive | Caenorhabditis elegans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Caenorhabditis elegans | |
| 0.0027 | - |
L-Orn | - |
Caenorhabditis elegans | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Caenorhabditis elegans | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
| Haemonchus contortus | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Caenorhabditis elegans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Orn | - |
Caenorhabditis elegans | Putrescine + CO2 | - |
? | |
| L-Orn | - |
Haemonchus contortus | Putrescine + CO2 | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | 42 | - |
Caenorhabditis elegans |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | 45 | no activity below 22°C, activity is sharply diminished above 45°C | Caenorhabditis elegans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | 8 | - |
Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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