Application | Comment | Organism |
---|---|---|
medicine | incubation of rat hippocampal slices with the potassium channel antagonis tetraethyl ammonium results in widespread excitotoxic death of pyramidal and granule cell neurons. Treatment with bacterial enzyme significantly reduces excitotoxicity induced by tetraethyl ammonium without showing neurotoxicity. Targeting of enzyme to the interior of synaptic vesicles may enhance its potency as a neuroprotectant | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52500, SDS-PAGE, x * 52000, calculated | Escherichia coli |
52500 | - |
x * 52500, SDS-PAGE, x * 52000, calculated | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
71 | 86 | - |
Escherichia coli |
Storage Stability | Organism |
---|---|
-20°C, stable for several months without loss of activity | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate | - |
Escherichia coli | 4-aminobutanoate + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 52500, SDS-PAGE, x * 52000, calculated | Escherichia coli |