Inhibitors | Comment | Organism | Structure |
---|---|---|---|
citrate | 50% inhibition of mitochondrial enzyme at 4.5 mM | Rattus norvegicus | |
coenzyme A | 50% inhibition of mitochondrial enzyme at 0.05 mM | Rattus norvegicus | |
phosphoenolpyruvate | 50% inhibition of mitochondrial enzyme at 28 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
oxaloacetate | - |
Rattus norvegicus | |
0.23 | - |
oxaloacetate | mitochondrial enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | differs from mitochondrial enzyme | Rattus norvegicus | 5737 | - |
microsome | - |
Rattus norvegicus | - |
- |
mitochondrion | differs from cytoplasmic enzyme | Rattus norvegicus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | only cytoplasmic enzyme | Rattus norvegicus | |
Mn2+ | only cytoplasmic enzyme | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
oxaloacetate | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Oxaloacetate | - |
Rattus norvegicus | Pyruvate + CO2 | - |
? | |
oxaloacetate | - |
Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
enzyme assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
cytoplasmic enzyme | Rattus norvegicus |
9.5 | - |
mitochondrial enzyme | Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 10 | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
28 | - |
phosphoenolpyruvate | mitochondrial enzyme | Rattus norvegicus |