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Literature summary for 4.1.1.1 extracted from
- Molecular and functional characterization of two pyruvate decarboxylase genes, PDC1 and PDC5, in the thermotolerant yeast Kluyveromyces marxianus (2018), Appl. Microbiol. Biotechnol., 102, 3723-3737 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Kluyveromyces marxianus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Kluyveromyces marxianus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 10 mM used in assay conditions | Kluyveromyces marxianus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | Kluyveromyces marxianus | - |
acetaldehyde + CO2 | - |
? | |
| pyruvate | Kluyveromyces marxianus KCTC 17555 | - |
acetaldehyde + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Kluyveromyces marxianus | - |
- |
- |
| Kluyveromyces marxianus KCTC 17555 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| MBPTrap column chromatography | Kluyveromyces marxianus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | isoform Pdc5p lacks enzymatic activity | Kluyveromyces marxianus | ? | - |
? | |
| additional information | isoform Pdc5p lacks enzymatic activity | Kluyveromyces marxianus KCTC 17555 | ? | - |
? | |
| pyruvate | - |
Kluyveromyces marxianus | acetaldehyde + CO2 | - |
? | |
| pyruvate | - |
Kluyveromyces marxianus KCTC 17555 | acetaldehyde + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 103400, maltose binding protein-bound isoform Pdc1p, calculated from amino acid sequence | Kluyveromyces marxianus |
| ? | x * 104900, maltose binding protein-bound isoform Pdc5p, calculated from amino acid sequence | Kluyveromyces marxianus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDC1 | isoform | Kluyveromyces marxianus |
| Pdc1p | isoform | Kluyveromyces marxianus |
| Pdc5 | isoform | Kluyveromyces marxianus |
| Pdc5p | isoform | Kluyveromyces marxianus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Kluyveromyces marxianus | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Kluyveromyces marxianus | the expression of isoform PDC1 is enhanced by D-glucose | up |
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Release 2023.1 (January 2023)
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