Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | PDC1 is expressed during aerobic growth on glucose and is upregulated 4fold in response to oxygen limitation, PDC1 expression is lower in cells grown on ethanol and succinate than on glucose and is up regulated 2-4fold, respectively, after glucose addition | Wickerhamomyces anomalus |
Cloned (Comment) | Organism |
---|---|
gene pdc1, DNA and amino acid sequence determination and analysis, cloning of the flanking regions, expression analysis, enzyme expression is regulated by hypoxia and carbon source but posttranscriptional regulation may play a major role in regulating the metabolic flux, PDC1 is expressed during aerobic growth on glucose and is upregulated 4fold in response to oxygen limitation, PDC1 expression is lower in cells grown on ethanol and succinate than on glucose and is up regulated 2-4fold, respectively, after glucose addition | Wickerhamomyces anomalus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Wickerhamomyces anomalus | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Wickerhamomyces anomalus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | Wickerhamomyces anomalus | enzyme expression is regulated by hypoxia and carbon source but posttranscriptional regulation may play a major role in regulating the metabolic flux | acetaldehyde + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Wickerhamomyces anomalus | Q659I2 | i.e. Candida pelliculosa or Hansenula anomala, diploid type strain NRRL-Y-366, haploid strain NRRL-Y-366-8, gene pdc1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | - |
Wickerhamomyces anomalus | acetaldehyde + CO2 | - |
? | |
pyruvate | enzyme expression is regulated by hypoxia and carbon source but posttranscriptional regulation may play a major role in regulating the metabolic flux | Wickerhamomyces anomalus | acetaldehyde + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDC1 | - |
Wickerhamomyces anomalus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | - |
Wickerhamomyces anomalus |