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Literature summary for 3.9.1.1 extracted from

  • Parvin, R.; Smith, R.A.
    Phosphoramidates. V. probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase (1969), Biochemistry, 8, 1748-1755.
    View publication on PubMed
Search for more literature for 3.9.1.1

General Stability

General Stability Organism
enzyme is active for more than 5 h, shows activity even at 0°C Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
molybdate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
13
-
 Phosphoramidate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
N-phosphocreatine + H2O = creatine + phosphate reaction mechanism Rattus norvegicus
a

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.16
-
 substrate phosphoramidate, enzyme source kidney microsomes Rattus norvegicus
0.181
-
 substrate phosphoramidate, enzyme source liver microsomes Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoramidate + H2O
-
 Rattus norvegicus NH4+ + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
More
-
-

pH Stability

pH Stability pH Stability Maximum Comment Organism
5
-
 pretreatment with pH 5.0 reduces activity 25fold Rattus norvegicus
9.7
-
 pretreatment with pH 9.7 increases activity 1.4fold, KM decreases 5.7fold Rattus norvegicus