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Literature summary for 3.7.1.3 extracted from

  • Shetty, A.S.; Gaertner, F.H.
    Kynureninase-type enzymes of Penicillium roqueforti, Aspergillus niger, Rhizopus stolonifer, and Pseudomonas fluorescens: Further evidence for distinct kynureninase and hydroxykynureninase activities (1975), J. Bacteriol., 122, 235-244.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.7.1.3

Application

Application Comment Organism
medicine tryptophan metabolism Aspergillus niger
medicine tryptophan metabolism Pseudomonas fluorescens
medicine tryptophan metabolism Penicillium roqueforti
medicine tryptophan metabolism Rhizopus stolonifer

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0039
-
 3-hydroxy-L-kynurenine
-
 Aspergillus niger
0.0046
-
 3-hydroxy-L-kynurenine
-
 Penicillium roqueforti
0.0067
-
 3-hydroxy-L-kynurenine
-
 Rhizopus stolonifer
0.01
-
 kynurenine
-
 Penicillium roqueforti
0.025
-
 kynurenine
-
 Rhizopus stolonifer
0.08
-
 kynurenine
-
 Aspergillus niger

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-L-kynurenine + H2O Aspergillus niger
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O Pseudomonas fluorescens
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O Penicillium roqueforti
-
 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O Rhizopus stolonifer
-
 3-hydroxyanthranilate + L-Ala
-
 ?
L-kynurenine + H2O Aspergillus niger
-
 anthranilate + L-alanine
-
 ?
L-kynurenine + H2O Pseudomonas fluorescens
-
 anthranilate + L-alanine
-
 ?
L-kynurenine + H2O Penicillium roqueforti
-
 anthranilate + L-alanine
-
 ?
L-kynurenine + H2O Rhizopus stolonifer
-
 anthranilate + L-alanine
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-
Penicillium roqueforti
-
-
-
Pseudomonas fluorescens
-
-
-
Rhizopus stolonifer
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus niger
-
 Pseudomonas fluorescens
-
 Penicillium roqueforti
-
 Rhizopus stolonifer

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-L-kynurenine + H2O
-
 Aspergillus niger 3-hydroxyanthranilate + L-alanine
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Pseudomonas fluorescens 3-hydroxyanthranilate + L-alanine
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Penicillium roqueforti 3-hydroxyanthranilate + L-alanine
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Rhizopus stolonifer 3-hydroxyanthranilate + L-alanine
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Aspergillus niger 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Pseudomonas fluorescens 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Penicillium roqueforti 3-hydroxyanthranilate + L-Ala
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Rhizopus stolonifer 3-hydroxyanthranilate + L-Ala
-
 ?
L-kynurenine + H2O
-
 Aspergillus niger anthranilate + L-alanine
-
 ?
L-kynurenine + H2O
-
 Pseudomonas fluorescens anthranilate + L-alanine
-
 ?
L-kynurenine + H2O
-
 Penicillium roqueforti anthranilate + L-alanine
-
 ?
L-kynurenine + H2O
-
 Rhizopus stolonifer anthranilate + L-alanine
-
 ?