Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.7.1.2 extracted from

  • Kvittingen, E.A.; Rootwelt, H.; Brandtzaeg, P.; Bergan, A.; Berger, R.
    Hereditary tyrosinemia type I (1993), J. Clin. Invest., 91, 1816-1821.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.7.1.2

Application

Application Comment Organism
medicine plays a role in hereditary tyrosinemia Homo sapiens
medicine plays a role in degradation pathway of phenylalanine and tyrosine Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.8 1.2 Fumarylacetoacetate liver, dependent on patients Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0004 0.032 liver, dependent on patients Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-fumarylacetoacetate + H2O
-
 Homo sapiens acetoacetate + fumarate
-
 ?