Any feedback?
Literature summary for 3.6.5.4 extracted from
- Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation (2007), J. Cell Biol., 178, 611-620.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| A143W | mutant, GTPase activation defective | Escherichia coli |
| A144W | mutant, GTPase activation defective | Escherichia coli |
| A335W | mutant, GTPase activation defective | Escherichia coli |
| A336W | mutant, GTPase activation defective | Escherichia coli |
| E475K | mutant, complex formation defective | Escherichia coli |
| G455W | mutant, complex formation defective | Escherichia coli |
| K399A | mutant, complex formation defective | Escherichia coli |
| N302A | mutant, GTPase activation defective | Escherichia coli |
| Q109A | mutant, GTPase activation defective | Escherichia coli |
| R141A | mutant, GTPase activation defective | Escherichia coli |
| R194A | mutant, GTPase activation defective | Escherichia coli |
| R333A | mutant, GTPase activation defective | Escherichia coli |
| R386A | mutant, GTPase activation defective | Escherichia coli |
| T307A | mutant, complex formation and GTPase activation defective | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | microsomal membrane | Escherichia coli | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Escherichia coli |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Escherichia coli | - |
GDP + phosphate | - |
ir | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| ribonucleoprotein | the Ffh protein binds to the 4.5S SRP RNA | Escherichia coli |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Escherichia coli | GDP + phosphate | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | SRP-FtsY complex | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ffh | - |
Escherichia coli |
| FtsY | - |
Escherichia coli |
| signal recognition particle | - |
Escherichia coli |
| signal recognition particle receptor | - |
Escherichia coli |
| SRP | - |
Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
