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Literature summary for 3.6.5.4 extracted from
- The signal recognition particle receptor alpha subunit of the hyperthermophilic archaeon Acidianus ambivalens exhibits an intrinsic GTP-hydrolyzing activity (1997), Biochim. Biophys. Acta, 1335, 218-230.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | protein translocation across the endoplasmic reticulum | Acidianus ambivalens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Acidianus ambivalens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D329A | diminished GTPase activity | Acidianus ambivalens |
| T326N | diminished GTPase activity | Acidianus ambivalens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | SRP receptor alpha subunit | Acidianus ambivalens | 5783 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Acidianus ambivalens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42200 | - |
SRP receptor subunit alpha, DNA sequence analysis | Acidianus ambivalens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Acidianus ambivalens | - |
GDP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acidianus ambivalens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Acidianus ambivalens | GDP + phosphate | - |
? | |
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