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Literature summary for 3.6.5.3 extracted from
- An inhibitor of elongation factor G (EF-G) GTPase present in the ribosome wash of Escherichia coli: a complex of initiation factors IF1 and IF3? (1992), Biochim. Biophys. Acta, 1129, 145-148.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ribosomal subunits | - |
Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EF-G GTPase inhibitor | - |
Escherichia coli | |
| translation initiation factor IF1 | - |
Escherichia coli | |
| translation initiation factor IF3 | inhibition could be overcome by increasing concentrations of divalent cations | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Escherichia coli | - |
GDP + phosphate | - |
? |  |
| GTP + H2O | Escherichia coli B / ATCC 11303 | - |
GDP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
elongation facor G ((EF)G) | - |
| Escherichia coli B / ATCC 11303 | - |
elongation facor G ((EF)G) | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Escherichia coli | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Escherichia coli B / ATCC 11303 | GDP + phosphate | - |
? | |
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