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Literature summary for 3.6.5.2 extracted from
- Characterization of Rab18, a lipid droplet-associated small GTPase (2008), Methods Enzymol., 438, 109-129.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| N122I | mutant with nucleotide deficiency | Mus musculus |
| Q67L | mutant with constitutive GTP binding and activation deficiency | Mus musculus |
| S22N | mutant with constitutive GDP binding deficiency | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | in 3T3-L1 adipocytes, stimulation of lipolysis increases the association of Rab18 with lipid droplets, suggesting that recruitment of Rab18 is regulated by the metabolic state of individual lipid droplets | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| 3T3-L1 cell | - |
Mus musculus | - |
| adipocyte | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Mus musculus | GDP + phosphate | - |
? | |
| additional information | in 3T3-L1 adipocytes, stimulation of lipolysis increases the association of Rab18 with lipid droplets, suggesting that recruitment of Rab18 is regulated by the metabolic state of individual lipid droplets | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Rab18 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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