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Literature summary for 3.6.5.2 extracted from

  • Yin, J.; Lu, J.; Yu, F.S.
    Role of small GTPase Rho in regulating corneal epithelial wound healing (2008), Invest. Ophthalmol. Vis. Sci., 49, 900-909.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
heparin-binding epidermal growth factor-like growth factor induces rapid and strong RhoA activation Homo sapiens
heparin-binding epidermal growth factor-like growth factor induces rapid and strong RhoA activation Sus scrofa
lysophosphatidic acid induces rapid and strong RhoA activation Homo sapiens
lysophosphatidic acid induces rapid and strong RhoA activation Sus scrofa
additional information wounding induces rapid and strong RhoA activation Homo sapiens
additional information wounding induces rapid and strong RhoA activation Sus scrofa

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 cells Homo sapiens
expressed in Escherichia coli BL21 cells Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
Clostridium botulinum exoenzyme C3 specific inhibitor Homo sapiens
Clostridium botulinum exoenzyme C3 specific inhibitor Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding ?
-
?
additional information Sus scrofa RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
corneal epithelial cell
-
Homo sapiens
-
corneal epithelial cell
-
Sus scrofa
-
THCE cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding Homo sapiens ?
-
?
additional information RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
Rho
-
Homo sapiens
Rho
-
Sus scrofa
RhoA
-
Homo sapiens
RhoA
-
Sus scrofa