Cloned (Comment) | Organism |
---|---|
into pcDNA3.1 vector for transfection of HEK-293 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
CFP-TM-Galpha | consists of a cleavable signal peptide from human growth hormone, enhanced CFP, the amino-terminal amino acids of the rat mu-opioid receptor, including TM1 and intracellular loop1, and the human Galpha subunit | Homo sapiens |
CFP-TM-Galphai3 | C to G mutation at the -4 position to render them insensitive to PTX-mediated ADP-ribosylation | Homo sapiens |
CFP-TM-GalphaoA | C to G mutation at the -4 position to render them insensitive to PTX-mediated ADP-ribosylation | Homo sapiens |
CFP-TM-GalphaQ205L | active mutant | Homo sapiens |
CFP-TM-Galphasq5 | the five aminoacids normally found in the carboxyl terminus of Galphas, QYELL, are replaced with those normally found in the carboxy terminus of Galphaq, EYNLV | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotrimer | Galpha subunit, GDP-bound inactive, GTP-bound active and betagamma dimer | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
GTP phosphohydrolase | - |
Homo sapiens |
heterotrimeric G-protein GTPase | - |
Homo sapiens |