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Literature summary for 3.6.5.1 extracted from
- Regulation of transducin GTPase activity by human retinal RGS (1997), J. Biol. Chem., 272, 17444-17449.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| gamma-subunit of cGMP phosphodiesterase | accelerate GTP hydrolysis by transducin | Homo sapiens | |
| RGS | retinal specific member of the RGS family accelerates GTP hydrolysis by transducin | Homo sapiens |  |
| unidentified membrane factor | accelerate GTP hydrolysis by transducin | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Homo sapiens | intrinsic GTPase activity of transducin controls inactivation of the effector enzyme, cGMP phosphodiesterase during turnoff of the visual signal | GDP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
transducin GTPase activity | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| retina | outer rod segment | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | intrinsic GTPase activity of transducin controls inactivation of the effector enzyme, cGMP phosphodiesterase during turnoff of the visual signal | Homo sapiens | GDP + phosphate | - |
? | |
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