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Literature summary for 3.6.4.6 extracted from

  • Finken-Eigen, M.; Roehricht, R.A.; Koehrer, K.
    The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment (1997), Curr. Genet., 31, 469-480.
    View publication on PubMed
Search for more literature for 3.6.4.6

Cloned(Commentary)

Cloned (Comment) Organism
constructing of a genomic library from the haploid yeast strain SD228-7 using the Escherichia coli-yeast shuttle vector pCS19 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Saccharomyces cerevisiae 5829
-
endoplasmic reticulum
-
 Homo sapiens 5783
-
endoplasmic reticulum
-
 Saccharomyces cerevisiae 5783
-
Golgi apparatus
-
 Homo sapiens 5794
-
Golgi apparatus
-
 Saccharomyces cerevisiae 5794
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48100
-
 predicted from amino acid sequence Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Mus musculus
-
 ADP + phosphate
-
 ?
ATP + H2O Homo sapiens
-
 ADP + phosphate
-
 ?
ATP + H2O Saccharomyces cerevisiae
-
 ADP + phosphate
-
 ?
ATP + H2O Schizosaccharomyces pombe
-
 ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-
Mus musculus
-
-
-
Saccharomyces cerevisiae
-
-
-
Schizosaccharomyces pombe
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Mus musculus
a
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Homo sapiens
a
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Saccharomyces cerevisiae
a
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Schizosaccharomyces pombe
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Mus musculus ADP + phosphate
-
 ?
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ?
ATP + H2O
-
 Saccharomyces cerevisiae ADP + phosphate
-
 ?
ATP + H2O
-
 Schizosaccharomyces pombe ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
NSF protein
-
 Homo sapiens
NSF protein
-
 Saccharomyces cerevisiae
SKD1
-
 Mus musculus
SKD1
-
 Schizosaccharomyces pombe
VPS4 gene product
-
 Saccharomyces cerevisiae