Literature summary for 3.6.4.13 extracted from

Tsai-Morris, C.H.; Sheng, Y.; Gutti, R.; Li, J.; Pickel, J.; Dufau, M.L.
Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) gene: cell-specific expression and transcriptional regulation by androgen in transgenic mouse testis (2010), J. Cell. Biochem., 109, 1142-1147.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	transgenic	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Leydig cell	the 1 kb fragment (5' to the ATG codon) of GRTH gene contains sequences for androgen regulation of its expression in Leydig cells	Mus musculus	-
testis	the expression of GRTH in testicular cells is differentially regulated by its 5' flanking sequence	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
gonadotropin-regulated testicular RNA helicase	-	Mus musculus
GRTH	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	GRTH gene expression is transcriptionally upregulated by human chorionic gonadotropin (hCG) via second messenger (cAMP) and androgen in Leydig cells. The expression of GRTH in testicular cells is differentially regulated by its 5' flanking sequence. The 1 kb fragment of GRTH gene (5' to the ATG codon) contains sequences for androgen regulation of its expression in Leydig cells	up

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Release 2023.1 (January 2023)