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Literature summary for 3.6.4.10 extracted from
- Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine (2009), EMBO J., 28, 602-613.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E12C | C for fluorescent labelling | Escherichia coli |
| E12C/C-terminal truncation | containing residue 1-496, monomeric | Escherichia coli |
| E12C/E34A | mutant hydrolyses ATP about 10-times more slowly than wild-type protein, C for fluorescent labelling | Escherichia coli |
| E34A | mutant hydrolyses ATP about 10-times more slowly than wild-type protein | Escherichia coli |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.25 | - |
ATP | at 30°C | Escherichia coli |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Escherichia coli | ADP + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | - |
Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| chaperone hsp90 | - |
Escherichia coli |
| HtpG | - |
Escherichia coli |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.011 | - |
ATP | at 30°C | Escherichia coli | |
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Release 2023.1 (January 2023)
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