Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Rattus norvegicus | |
additional information | no inhibition by gadolinium chloride, levamisole, heparin, and lysophosphatidic acid in the soluble and microsomal fractions | Rattus norvegicus | |
suramin | a P2 receptor antagonist and an inhibitor of E-NTPDase and NPP1-2 activities | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0919 | - |
4-nitrophenyl-5'-TMP | microsomal fraction, pH 8.9, 37°C | Rattus norvegicus | |
0.1185 | - |
4-nitrophenyl-5'-TMP | soluble fraction, pH 8.9, 37°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | higher activity than in the soluble fraction | Rattus norvegicus | - |
- |
soluble | lower activity than in the microsomal fraction | Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male | - |
Rattus norvegicus Wistar | - |
male | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl-5'-TMP + H2O | - |
Rattus norvegicus | 4-nitrophenol + 5'-TMP | - |
? | |
4-nitrophenyl-5'-TMP + H2O | - |
Rattus norvegicus Wistar | 4-nitrophenol + 5'-TMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
E-NPP | - |
Rattus norvegicus |
ectonucleotide pyrophosphatase/phosphodiesterase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.9 | - |
soluble fraction | Rattus norvegicus |
9.3 | - |
microsomal fraction | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme might be involved in nucleotide signalling in the cardiac tissue | Rattus norvegicus |