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Literature summary for 3.6.1.59 extracted from

  • Liu, H.; Rodgers, N.D.; Jiao, X.; Kiledjian, M.
    The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases (2002), EMBO J., 21, 4699-4708.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.59

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38600
-
 x * 38600, calculated from sequence Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
m7G5'ppp5'N(3'ppp5'N)n + H2O Homo sapiens n = 1-8 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?
m7G5'ppp5'N(3'ppp5'N)n + H2O Saccharomyces cerevisiae n = 1-8 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96C86
-
-
Saccharomyces cerevisiae Q06151
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
K-562 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
m7G5'ppp5'N(3'ppp5'N)n + H2O n = 1-8 Homo sapiens 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?
m7G5'ppp5'N(3'ppp5'N)n + H2O n = 1-8 Saccharomyces cerevisiae 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?
m7G5'ppp5'N(3'ppp5'N)n + H2O n = 1-8, DcpS is capable of acting on an mRNA once it is degraded down to 10 nuceotides Homo sapiens 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?
m7G5'ppp5'N(3'ppp5'N)n + H2O n = 1-8, the recombinant protein specifically hydrolyzes methylated cap analog but does not hydrolyze unmethylated cap analog nor does it function on intact capped RNA. DcpS is capable of acting on an mRNA once it is degraded down to 10 nucleotides Homo sapiens 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
-
 ?
additional information Dcps shows no activity with 7-methylguanosine 5'-diphosphate Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 38600, calculated from sequence Homo sapiens

Synonyms

Synonyms Comment Organism
Dcps
-
 Homo sapiens
yDcps
-
 Saccharomyces cerevisiae
YLR270W
-
 Saccharomyces cerevisiae