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Literature summary for 3.6.1.52 extracted from

  • Wu, M.; Chong, L.S.; Capolicchio, S.; Jessen, H.J.; Resnick, A.C.; Fiedler, D.
    Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues (2014), Angew. Chem. Int. Ed. Engl., 53, 7192-7197.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,4,5,6-pentaphosphate competitive Homo sapiens
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate competitive Homo sapiens
inositol 4-butyl-1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate competitive Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O95989
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphoinositol polyphosphate + H2O
-
Homo sapiens inositol polyphosphate + phosphate
-
?
P1,P5-bis(5'-adenosyl)pentaphosphate + H2O
-
Homo sapiens AMP + adenosine 5'-tetraphosphate reaction of EC 3.6.1.17 ?

Synonyms

Synonyms Comment Organism
DIPP1
-
Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000023
-
inositol 4-butyl-1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate pH not specified in the publication, temperature not specified in the publication Homo sapiens
0.00011
-
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,4,5,6-pentaphosphate pH not specified in the publication, temperature not specified in the publication Homo sapiens
0.00027
-
inositol 1-[(phosphorylmethyl)phosphonic acid]-2,3,5,6-tetraphosphate pH not specified in the publication, temperature not specified in the publication Homo sapiens