Literature summary for 3.6.1.52 extracted from

Caffrey, J.J.; Safrany, S.T.; Yang, X.; Shears, S.B.
Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding NUDT family (2000), J. Biol. Chem., 275, 12730-12736.

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Cloned(Commentary)

Cloned (Comment)	Organism
isoenzyme hDIPP2alpha and hDIPP2beta	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0000042	-	diphosphoinositol pentakisphosphate	isoenzyme hDIPP1 and hDIPP2alpha	Homo sapiens
0.0000048	-	diphosphoinositol pentakisphosphate	isoenzyme hDIPP2beta	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
20434	-	x * 20434, calculation from nucleotide sequence	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	isoenzyme hDIPP1, hDIPP2alpha and hDIPP2beta	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
diphosphoinositol pentakisphosphate + H2O	-	Homo sapiens	inositol hexakisphosphate + phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 20434, calculation from nucleotide sequence	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.03	-	diphosphoinositol pentakisphosphate	isoenzyme hDIPP2beta	Homo sapiens
0.15	-	diphosphoinositol pentakisphosphate	isoenzyme hDIPP2alpha	Homo sapiens
0.2	-	diphosphoinositol pentakisphosphate	isoenzyme hDIPP1	Homo sapiens

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Release 2023.1 (January 2023)