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Literature summary for 3.6.1.5 extracted from
- Immunocytochemical localization of NTPDases1 and 2 in the neural retina of mouse and zebrafish (2009), Synapse, 63, 291-307.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | analyzed in presence and absence of, control reaction | Danio rerio |  |
| EDTA | analyzed in presence and absence of, control reaction | Mus musculus | |
| additional information | discrimination between total ATPase activity and ecto-ATPase activity by using vanadate, oligomycin and N-ethylmaleimide as inhibitors of ATPases of type P, F and V to focus on ecto-ATPase activity | Danio rerio | |
| additional information | discrimination between total ATPase activity and ecto-ATPase activity by using vanadate, oligomycin and N-ethylmaleimide as inhibitors of ATPases of type P, F and V to focus on ecto-ATPase activity | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Danio rerio | - |
ADP + phosphate | - |
? | |
| ATP + H2O | Mus musculus | - |
ADP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Danio rerio | - |
- |
- |
| Mus musculus | P55772 | Swiss strain, male | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ganglion | absent from Müller glia | Danio rerio | - |
| horizontal cell | NTPDases 1 and 2 differentially localized in | Danio rerio | - |
| inner plexiform layer | - |
Danio rerio | - |
| inner plexiform layer | diffuse labelling of | Mus musculus | - |
| neuron | activity on surface of | Mus musculus | - |
| outer plexiform layer | - |
Danio rerio | - |
| outer plexiform layer | sharp thin band in, mainly restricted to horizontal cell processes in | Mus musculus | - |
| photoreceptor | photoreceptor segments, NTPDases 1 and 2 differentially localized in | Danio rerio | - |
| retina | - |
Danio rerio | - |
| retina | expression in, also in intraretinal blood vessels of, no expression in Müller glia, highly in optic fiber bundles | Mus musculus | - |
| retinal ganglion cell | expression in | Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
immunocytochemical localization in retinal layers, compartmentalized regulation of extracellular nucleotide/nucleoside concentration in the retinal layers, potential role for extracellular nucleotide mediated-signaling in the retina of vertebrates | Danio rerio |
| additional information | - |
immunocytochemical localization in retinal layers, compartmentalized regulation of extracellular nucleotide/nucleoside concentration in the retinal layers, potential role for extracellular nucleotide mediated-signaling in the retina of vertebrates | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Danio rerio | ADP + phosphate | - |
? | |
| ATP + H2O | - |
Mus musculus | ADP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| E-NTPDase | - |
Danio rerio |
| E-NTPDase | - |
Mus musculus |
| ectonucleoside triphosphate diphosphohydrolase | - |
Danio rerio |
| ectonucleoside triphosphate diphosphohydrolase | - |
Mus musculus |
| NTPDase1 | - |
Danio rerio |
| NTPDase1 | - |
Mus musculus |
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