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Literature summary for 3.6.1.5 extracted from

  • Bruno, A.N.; Bonan, C.D.; Wofchuk, S.T.; Sarkis, J.J.; Battastini, A.M.
    ATP diphosphohydrolase (NTPDase 1) in rat hippocampal slices and effect of glutamate on the enzyme activity in different phases of development (2002), Life Sci., 71, 215-225.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
L-glutamate activation of ATP hydrolysis, no activation of ADP hydrolysis Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.141
-
 ATP pH 7.4, 37°C, presence of Ca2+ Rattus norvegicus
0.167
-
 ADP pH 7.4, 37°C, presence of Ca2+ Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activation Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Rattus norvegicus AMP + phosphate
-
 ?
ATP + 2 H2O
-
 Rattus norvegicus AMP + 2 phosphate
-
 ?