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Literature summary for 3.6.1.5 extracted from
- Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8 (2004), Biochemistry, 43, 5511-5519.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Mus musculus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.013 | - |
ATP | pH 7.4, 37°C | Mus musculus |  |
| 0.041 | - |
ADP | pH 7.4, 37°C | Mus musculus | |
| 0.047 | - |
UTP | pH 7.4, 37°C | Mus musculus | |
| 0.171 | - |
UDP | pH 7.4, 37°C | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Mus musculus | 5886 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | absolute requirement for divalent cation, Ca2+ fulfilling requirement best | Mus musculus | |
| Mg2+ | absolute requirement for divalent cation, Ca2+ fulfilling requirement best | Mus musculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 54650 | - |
x * 54650, deduced from gene sequence | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q8K0L2 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | amino acid sequence shows eight putative N-glycosilation sites | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| jejunum | - |
Mus musculus | - |
| kidney | - |
Mus musculus | - |
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + H2O | - |
Mus musculus | AMP + phosphate | - |
? | |
| ATP + 2 H2O | - |
Mus musculus | AMP + 2 phosphate | - |
? | |
| UDP + H2O | - |
Mus musculus | UMP + phosphate | - |
? | |
| UTP + 2 H2O | - |
Mus musculus | UMP + 2 phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 54650, deduced from gene sequence | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.4 | - |
hydrolysis of ADP | Mus musculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 8 | hydrolysis of ATP | Mus musculus |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Mus musculus | calculated from amino acid sequence | - |
6 |
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