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Literature summary for 3.6.1.5 extracted from

  • Beaudoin, A.R; Sevigny, J.; Grondin, G.; Daoud, S.; Levesque, F.P.
    Purification, characterization, and localisation of two ATP diphosphohydrolase isoforms in bovine heart (1997), Am. J. Physiol., 273, 673-681.
No PubMed abstract available
Search for more literature for 3.6.1.5

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibition by orthovanadate; no inhibition by ouabain; no inhibition by P1,P5-di(adenosine-5'-)pentanphospate Bos taurus
NaN3
-
 Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.029
-
 ADP
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ either Mg2+ or Ca2+ required for activity Bos taurus
Mg2+ either Mg2+ or Ca2+ required for activity Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
-
 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Bos taurus
-
 AMP + phosphate
-
 ?
ATP + 2 H2O Bos taurus
-
 AMP + 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
two ATPDase isoforms Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
heart ventricle, detected by immunoblotting in smooth muscle cells and endothelial cells Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Bos taurus AMP + phosphate
-
 ?
ATP + 2 H2O
-
 Bos taurus AMP + 2 phosphate
-
 ?
CDP + H2O
-
 Bos taurus CMP + phosphate
-
 ?
CTP + 2 H2O
-
 Bos taurus CMP + 2 phosphate
-
 ?
GTP + 2 H2O
-
 Bos taurus GMP + 2 phosphate
-
 ?
ITP + 2 H2O
-
 Bos taurus IMP + 2 phosphate
-
 ?
additional information no hydrolysis of GMP, UMP Bos taurus ?
-
 ?
additional information neglible hydrolysis of AMP Bos taurus ?
-
 ?
UDP + H2O
-
 Bos taurus UMP + phosphate
-
 ?
UTP + 2 H2O
-
 Bos taurus UMP + 2 phosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Bos taurus