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Literature summary for 3.6.1.5 extracted from

  • Heine, P.; Braun, N.; Heilbronn, A.; Zimmermann, H.
    Functional characterization of rat ecto-ATPase and ecto-ATP diphosphohydrolase after heterologous expression in CHO cells (1999), Eur. J. Biochem., 262, 102-107.
    View publication on PubMed
Search for more literature for 3.6.1.5

Cloned(Commentary)

Cloned (Comment) Organism
expression in cells of chinese hamster ovaries Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
EDTA 1 mM Rattus norvegicus
Evans blue complete inhibition at 0.1 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane ectonucleotidase/ectoenzyme Rattus norvegicus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ either Mg2+ or Ca2+ required for activity Rattus norvegicus
Mg2+ either Mg2+ or Ca2+ required for activity Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000 80000 SDS-PAGE, immunoblotting Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Rattus norvegicus
-
 AMP + phosphate
-
 ?
ATP + 2 H2O Rattus norvegicus
-
 AMP + 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Rattus norvegicus AMP + phosphate
-
 ?
ADP + H2O 87% relative activity compared to ATP Rattus norvegicus AMP + phosphate
-
 ?
ATP + 2 H2O
-
 Rattus norvegicus AMP + 2 phosphate
-
 ?
ATP + 2 H2O 100% relative activity Rattus norvegicus AMP + 2 phosphate
-
 ?
CDP + H2O lowest relative activity with 61% Rattus norvegicus CMP + phosphate
-
 ?
CTP + 2 H2O
-
 Rattus norvegicus CMP + 2 phosphate
-
 ?
GDP + H2O
-
 Rattus norvegicus GMP + phosphate
-
 ?
GTP + 2 H2O
-
 Rattus norvegicus GMP + 2 phosphate
-
 ?
IDP + H2O
-
 Rattus norvegicus IMP + phosphate
-
 ?
ITP + 2 H2O
-
 Rattus norvegicus IMP + 2 phosphate
-
 ?
additional information neglible hydrolysis of AMP Rattus norvegicus ?
-
 ?
UDP + H2O
-
 Rattus norvegicus UMP + phosphate
-
 ?
UTP + 2 H2O
-
 Rattus norvegicus UMP + 2 phosphate
-
 ?