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Literature summary for 3.6.1.5 extracted from

  • LeBel, D.; Poirier, G.G.; Phaneuf, S.; St-Jean, P.; Laliberte, J.F.; Beaudoin, A.R.
    Characterization and purification of a calcium-sensitive ATP diphosphohydrolase from pig pancreas (1980), J. Biol. Chem., 255, 1227-1233.
    View publication on PubMed
Search for more literature for 3.6.1.5

Inhibitors

Inhibitors Comment Organism Structure
AMP
-
 Sus scrofa
Cibacron blue
-
 Sus scrofa
Ethacrynic acid
-
 Sus scrofa
N3-
-
 Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0073
-
 ATP
-
 Sus scrofa
0.0074
-
 ADP
-
 Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ either Mg2+ or Ca2+ required for activity Sus scrofa
Mg2+ either Mg2+ or Ca2+ required for activity Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
 SDS-PAGE Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Sus scrofa
-
 AMP + phosphate
-
 ?
ATP + 2 H2O Sus scrofa
-
 AMP + 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 pig
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
13
-
 ADP Sus scrofa
15.2
-
 ATP Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Sus scrofa AMP + phosphate
-
 ?
ATP + 2 H2O
-
 Sus scrofa AMP + 2 phosphate
-
 ?
CDP + H2O
-
 Sus scrofa CMP + phosphate
-
 ?
CTP + 2 H2O
-
 Sus scrofa CMP + 2 phosphate
-
 ?
GDP + H2O
-
 Sus scrofa GMP + phosphate
-
 ?
GTP + 2 H2O
-
 Sus scrofa GMP + 2 phosphate
-
 ?
IDP + H2O
-
 Sus scrofa IMP + phosphate
-
 ?
ITP + 2 H2O
-
 Sus scrofa IMP + 2 phosphate
-
 ?
additional information neglible hydrolysis of AMP Sus scrofa ?
-
 ?
UDP + H2O
-
 Sus scrofa UMP + phosphate
-
 ?
UTP + 2 H2O
-
 Sus scrofa UMP + 2 phosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Sus scrofa

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
37 75 37-45°C optimum, 75°C no activity Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9
-
 Sus scrofa