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Literature summary for 3.6.1.43 extracted from

  • Wedgwood, J.F.; Strominger, J.L.
    Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate (1980), J. Biol. Chem., 255, 1120-1123.
    View publication on PubMed
Search for more literature for 3.6.1.43

Activating Compound

Activating Compound Comment Organism Structure
EDTA
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
bacitracin no inhibition when preincubating with EDTA Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal ions required Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dolichyl diphosphate + H2O Homo sapiens involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate dolichyl phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphocyte RPMI 4265 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dolichyl diphosphate + H2O
-
 Homo sapiens dolichyl phosphate + phosphate
-
 ?
dolichyl diphosphate + H2O involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate Homo sapiens dolichyl phosphate + phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
7 9 95% and 90% of activity, broad pH-range Homo sapiens