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Literature summary for 3.6.1.29 extracted from
- Catabolism of Ap3A and Ap4A in human plasma. Purification and characterization of a glycoprotein complex with 5'-nucleotide phosphodiesterase activity (1985), Eur. J. Biochem., 149, 119-127.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Homo sapiens |  |
| Mn2+ | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0006 | - |
Ap4A | - |
Homo sapiens | |
| 0.001 | - |
P1-P3-bis(5'-adenosyl) triphosphate | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Homo sapiens | |
| Mg2+ | - |
Homo sapiens | |
| Zn2+ | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 230000 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| P1-P3-bis(5'-adenosyl) triphosphate + H2O | Homo sapiens | - |
ADP + AMP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | mannoside | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ap4A + H2O | - |
Homo sapiens | ? | - |
? | |
| ATP + 2 H2O | - |
Homo sapiens | AMP + 2 phosphate | - |
? | |
| diadenosine 5',5''-P1,P4-tetraphosphate + H2O | - |
Homo sapiens | AMP + ATP | - |
? | |
| NAD+ + H2O | - |
Homo sapiens | ? | - |
? | |
| P1-P3-bis(5'-adenosyl) triphosphate + H2O | - |
Homo sapiens | ADP + AMP | - |
? | |
| thymidine 5'-monophosphate p-nitrophenylester + H2O | - |
Homo sapiens | ? | - |
? | |
| UTP + 2 H2O | - |
Homo sapiens | UMP + 2 phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| polymer | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Homo sapiens |
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