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Literature summary for 3.6.1.23 extracted from
- Characterization and functional studies of fowl adenovirus 9 dUTPase (2016), Virology, 497, 251-261 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Fowl adenovirus 9 |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dUTP + H2O | Fowl adenovirus 9 | - |
dUMP + diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Fowl adenovirus 9 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Fowl adenovirus 9 |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dUTP + H2O | - |
Fowl adenovirus 9 | dUMP + diphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 22000, recombinant enzyme, SDS-PAGE | Fowl adenovirus 9 |
| ? | x * 17400, calculated from amino acid sequence | Fowl adenovirus 9 |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| deoxyuridine 5'-triphosphate pyrophosphatase | - |
Fowl adenovirus 9 |
| dUTPase | - |
Fowl adenovirus 9 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme upregulates the expression of type I interferons, but is not required for viral DNA or virus replication in CH-SAH cells | Fowl adenovirus 9 |
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