Application | Comment | Organism |
---|---|---|
medicine | potential drug target | Campylobacter jejuni |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) | Campylobacter jejuni |
Crystallization (Comment) | Organism |
---|---|
- |
Campylobacter jejuni |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required, three ions per subunit | Campylobacter jejuni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dUTP + H2O | Campylobacter jejuni | removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA | dUMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant protein | Campylobacter jejuni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dUTP + H2O | - |
Campylobacter jejuni | dUMP + diphosphate | - |
? | |
dUTP + H2O | removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA | Campylobacter jejuni | dUMP + diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | crystal structure analysis | Campylobacter jejuni |