KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00018 | - |
dUTP | - |
Escherichia coli | |
0.016 | - |
dUTP | - |
Escherichia coli | |
0.025 | - |
dUDP | - |
Escherichia coli | |
0.13 | - |
dUDP | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+ enhances binding to dUTPase of dUTP by a factor of 100 and dUDP by a factor of 10 | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dUTP + H2O | Escherichia coli | the enzyme prevents a deleterious incorporation of uracil into DNA | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
dUTP + H2O = dUMP + diphosphate | mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dUDP + H2O | - |
Escherichia coli | deoxyuridine + diphosphate | - |
? | |
dUTP + H2O | - |
Escherichia coli | dUMP + diphosphate | - |
? | |
dUTP + H2O | the enzyme prevents a deleterious incorporation of uracil into DNA | Escherichia coli | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
6 | 9 | dUTP | - |
Escherichia coli |