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Literature summary for 3.6.1.23 extracted from

  • Giroir, L.E.; Deutsch, W.A.
    Drosophila deoxyuridine triphosphatase. Purification and characterization (1987), J. Biol. Chem., 262, 130-134.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
Drosophila melanogaster
Ca2+
-
Drosophila melanogaster
EDTA
-
Drosophila melanogaster
EGTA
-
Drosophila melanogaster

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.001
-
dUTP
-
Drosophila melanogaster

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 0.5 mM, stimulates by 7% Drosophila melanogaster
Mg2+ metalloenzyme, may contain Mg2+, Mn2+ or both Drosophila melanogaster
Mn2+ metalloenzyme, may contain Mg2+, Mn2+ or both Drosophila melanogaster
Zn2+ 0.5 mM, stimulates by 7% Drosophila melanogaster

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
gel filtration, glycerol density gradient sedimentation Drosophila melanogaster

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
embryo embryos respresenting the only step in the life cycle of Drosophila with clearly detectable levels of the enzyme Drosophila melanogaster
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dUTP + H2O
-
Drosophila melanogaster dUMP + diphosphate
-
?

Subunits

Subunits Comment Organism
dimer 1 * 45000-50000, SDS-PAGE Drosophila melanogaster