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Literature summary for 3.6.1.23 extracted from

  • Williams, M.V.; Pollack, J.D.
    Purification and characterization of a dUTPase from Acholeplasma laidlawii B-PG9 (1984), J. Bacteriol., 159, 278-282.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.23

Inhibitors

Inhibitors Comment Organism Structure
EDTA reversed by Mg2+, Mn2+, Zn2+, Co2+ and Ca2+ Acholeplasma laidlawii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0045
-
 dUTP
-
 Acholeplasma laidlawii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 gel filtration Acholeplasma laidlawii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dUTP + H2O Acholeplasma laidlawii the enzyme is important in preventing dUTP from being incorporated into DNA and may have a significant role in both the synthesis of thymidine- and diphosphate-dependent phosphorylation ?
-
 ?
dUTP + H2O Acholeplasma laidlawii B-PG9 the enzyme is important in preventing dUTP from being incorporated into DNA and may have a significant role in both the synthesis of thymidine- and diphosphate-dependent phosphorylation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Acholeplasma laidlawii
-
 B-PG9
-
Acholeplasma laidlawii B-PG9
-
 B-PG9
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Acholeplasma laidlawii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dUTP + H2O
-
 Acholeplasma laidlawii dUMP + diphosphate
-
 ?
dUTP + H2O
-
 Acholeplasma laidlawii B-PG9 dUMP + diphosphate
-
 ?
dUTP + H2O the enzyme is important in preventing dUTP from being incorporated into DNA and may have a significant role in both the synthesis of thymidine- and diphosphate-dependent phosphorylation Acholeplasma laidlawii ?
-
 ?
dUTP + H2O the enzyme is important in preventing dUTP from being incorporated into DNA and may have a significant role in both the synthesis of thymidine- and diphosphate-dependent phosphorylation Acholeplasma laidlawii B-PG9 ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 1 h, stable Acholeplasma laidlawii