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Literature summary for 3.6.1.21 extracted from
- Nucleotide diphosphate hexose pyrophosphatases (1966), Biochem. Biophys. Res. Commun., 22, 524-531.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| intracellular inhibitor | can be destroyed by heating up to 58°C for a few min, inhibitor is resistant towards RNAse and DNAse and detectable at 280 nm | Escherichia coli | |
| intracellular inhibitor | can be destroyed by heating up to 58°C for a few min, inhibitor is resistant towards RNAse and DNAse and detectable at 280 nm | Salmonella weslaco |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| periplasm | - |
Escherichia coli | - |
- |
| periplasm | - |
Salmonella weslaco | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Escherichia coli |  |
| Mg2+ | - |
Salmonella weslaco | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP-sugar + H2O | Escherichia coli | - |
AMP + sugar phosphate | - |
? | |
| ADP-sugar + H2O | Salmonella weslaco | - |
AMP + sugar phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Salmonella weslaco | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.7 | - |
ADP-Glc with partially purified enzyme | Escherichia coli |
| 6.6 | 7.2 | ADP-Glc as substrate | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP-sugar + H2O | - |
Escherichia coli | AMP + sugar phosphate | - |
? | |
| ADP-sugar + H2O | - |
Salmonella weslaco | AMP + sugar phosphate | - |
? | |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 58 | - |
activation of the enzyme by inactivating an intracellular inhibitor | Escherichia coli |
| 58 | - |
activation of the enzyme by inactivating an intracellular inhibitor | Salmonella weslaco |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | - |
Escherichia coli |
| 7 | 8 | - |
Salmonella weslaco |
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Release 2023.1 (January 2023)
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