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Literature summary for 3.6.1.15 extracted from
- Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver (2004), World J. Gastroenterol., 10, 694-698.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| taurine | activates the enzyme, and acts as antagonist and reduces the hypochlorous acid toxicity | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HOCl | inhibits the muclear NTPase, taurine acts as antagonist and reduces the hypochlorous acid toxicity | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | nuclear envelope | Rattus norvegicus | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male sprague-dawley rats | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially, isolation of hepatic nuclei | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Rattus norvegicus | ADP + phosphate | - |
? | |
| GTP + H2O | preferred substrate | Rattus norvegicus | GDP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NTPase | - |
Rattus norvegicus |
| nucleoside triphosphatase | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Rattus norvegicus |
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