Literature summary for 3.6.1.14 extracted from

Guranowski, A.; Starzynska, E.; Pietrowska-Borek, M.; Jemielity, J.; Kowalska, J.; Darzynkiewicz, E.; Thompson, M.J.; Blackburn, G.M.
Methylene analogues of adenosine 5-tetraphosphate. Their chemical synthesis and recognition by human and plant mononucleoside tetraphosphatases and dinucleoside tetraphosphatases (2006), FEBS J., 273, 829-838.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no inhibition by alphabeta-methylene-adenosine 5'-tetraphosphate, betagamma-methylene adenosine 5'-tetraphosphate, gammadelta-methylene 5'-tetraphosphate, alphabeta-gammadelta-bismethylene-adenosine 5'-tetraphosphate, alphabeta-betagamma-bismethylene-adenosine 5'-tetraphosphate, and betagamma-gammadelta-bis(dichloro)methylene-adenosine 5'-tetraphosphate	Homo sapiens
additional information	no inhibition by alphabeta-methylene-adenosine 5'-tetraphosphate, betagamma-methylene adenosine 5'-tetraphosphate, gammadelta-methylene 5'-tetraphosphate, alphabeta-gammadelta-bismethylene-adenosine 5'-tetraphosphate, alphabeta-betagamma-bismethylene-adenosine 5'-tetraphosphate, and betagamma-gammadelta-bis(dichloro)methylene-adenosine 5'-tetraphosphate	Lupinus luteus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Lupinus luteus	-	yellow lupin	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-
seed	-	Lupinus luteus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
alpha-beta-methylene-adenosine 5'-tetraphosphate + H2O	-	Homo sapiens	alpha-beta-methylene-adenosine 5'-triphosphate + phosphate	-	?
alpha-beta-methylene-adenosine 5'-tetraphosphate + H2O	-	Lupinus luteus	alpha-beta-methylene-adenosine 5'-triphosphate + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
nucleoside tetraphosphatase	-	Homo sapiens
nucleoside tetraphosphatase	-	Lupinus luteus

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Release 2023.1 (January 2023)