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Literature summary for 3.6.1.12 extracted from

  • Gary, T.P.; Colowick, N.E.; Mosig, G.
    A species barrier between bacteriophages T2 and T4: exclusion, join-copy and join-cut-copy recombination and mutagenesis in the dCTPase genes (1998), Genetics, 148, 1461-1473.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Tequatrovirus T4
-
Escherichia phage T2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dCTP + H2O Tequatrovirus T4 the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4 dCMP + diphosphate
-
?
dCTP + H2O Escherichia phage T2 the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4 dCMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia phage T2
-
-
-
Tequatrovirus T4
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dCTP + H2O
-
Tequatrovirus T4 dCMP + diphosphate
-
?
dCTP + H2O
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Escherichia phage T2 dCMP + diphosphate
-
?
dCTP + H2O the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4 Tequatrovirus T4 dCMP + diphosphate
-
?
dCTP + H2O the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4 Escherichia phage T2 dCMP + diphosphate
-
?