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Literature summary for 3.6.1.1 extracted from

  • Mishra, D.R.; Chaudhary, S.; Krishna, B.M.; Mishra, S.K.
    Identification of critical elements for regulation of inorganic pyrophosphatase (PPA1) in MCF7 breast cancer cells (2015), PLoS ONE, 10, e0124864.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.1

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O Homo sapiens
-
 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q15181
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O
-
 Homo sapiens 2 phosphate
-
 ?

Synonyms

Synonyms Comment Organism
inorganic pyrophosphatase
-
 Homo sapiens
PPA1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens trichostatin A and Sp1 induce pyrophosphatase 1 promoter activity and protein expression up

General Information

General Information Comment Organism
malfunction knockdown of pyrophosphatase 1 decreases colony formation and viability of MCF-7 cells Homo sapiens