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Literature summary for 3.6.1.1 extracted from

  • Tezuka, Y.; Herai, N.; Inomata, Y.; Kagami, K.; Yamauchi, J.; Nishigori, H.; Sanbe, A.
    Upregulation of inorganic pyrophosphatase 1 as a JNK phosphatase in hypothyroid embryonic chick cerebellum (2015), Life Sci., 128, 94-100.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
x * 36000, SDS-PAGE Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
c-Jun N-terminale kinase + H2O Gallus gallus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebellum
-
Gallus gallus
-
embryo
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
c-Jun N-terminale kinase + H2O
-
Gallus gallus ?
-
?

Subunits

Subunits Comment Organism
? x * 36000, SDS-PAGE Gallus gallus

Synonyms

Synonyms Comment Organism
inorganic pyrophosphatase 1
-
Gallus gallus
PPA1
-
Gallus gallus

Expression

Organism Comment Expression
Gallus gallus inorganic pyrophosphatase 1 is upregulated in the chick cerebellum treated with methimazole at a dose of 0.02 mM/egg on day 14 up

General Information

General Information Comment Organism
physiological function the upregulation of the enzyme during neuronal development in the hypothyroid chick cerebellum may lead to impaired social behaviors as well as to impaired learning and memory via JNK dephosphorylation and inactivation in the chick cerebellum Gallus gallus