Literature summary for 3.5.5.1 extracted from

Barglow, K.T.; Saikatendu, K.S.; Bracey, M.H.; Huey, R.; Morris, G.M.; Olson, A.J.; Stevens, R.C.; Cravatt, B.F.
Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes (2008), Biochemistry, 47, 13514-13523.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Mus musculus

Crystallization (Commentary)

Crystallization (Comment)	Organism
isoform Nit2, to 1.4 A resolution. Modeling of activity-based proteomics probes Leu-Arg-alpha-chloroacetamide and Leu-Glu-alpha-chloroacetamide probes into the mNit2 active site	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
C191A	decrease/loss of labeling for activity-based proteomics probes	Mus musculus
F154A	decrease/loss of labeling for activity-based proteomics probes	Mus musculus
F164A	decrease/loss of labeling for activity-based proteomics probes	Mus musculus
F192A	decrease/loss of labeling for activity-based proteomics probes	Mus musculus
F217A	decrease/loss of labeling for activity-based proteomics probes	Mus musculus
Y192R	increase in labeling with proteomics probe Leu-Glu-alpha-CA probe	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	isoform Nit2	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant enzyme	Mus musculus

Synonyms

Synonyms	Comment	Organism
NIT2	-	Mus musculus

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Release 2023.1 (January 2023)