Application | Comment | Organism |
---|---|---|
synthesis | enzyme can be used as a biocatalyst for the synthesis of a range of alpha-hydroxy carboxylic acids or amides from aldehydes in presence of cyanide, halting of the reaction at the amide intermediate by use of specific inhibitors is possible | Rhodococcus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | - |
Rhodococcus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodococcus sp. | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a nitrile + 2 H2O = a carboxylate + NH3 | acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amines | Rhodococcus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-3-phenylpropionitrile + H2O | beta-substituted substrate | Rhodococcus sp. | 3-hydroxy-3-phenylpropionic acid + NH3 | - |
? | |
3-hydroxy-3-phenylpropionitrile + H2O | beta-substituted substrate | Rhodococcus sp. Novo SP361 | 3-hydroxy-3-phenylpropionic acid + NH3 | - |
? | |
additional information | substrate specificity profile, enzyme also catalyzes the synthesis of a range of alpha-hydroxy carboxylic acids or amides from aldehydes in presence of cyanide | Rhodococcus sp. | ? | - |
? | |
additional information | substrate specificity profile, enzyme also catalyzes the synthesis of a range of alpha-hydroxy carboxylic acids or amides from aldehydes in presence of cyanide | Rhodococcus sp. Novo SP361 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nitrile hydratase/amidase | - |
Rhodococcus sp. |