Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.5.1 extracted from

  • Almatawah, Q.A.; Cowan, D.A.
    Thermostable nitrilase catalysed production of nicotinic acid from 3-cyanopyridine (1999), Enzyme Microb. Technol., 25, 718-724.
No PubMed abstract available
Search for more literature for 3.5.5.1

General Stability

General Stability Organism
more resistant to thermal inactivation if cells immobilized in calcium alginate beads, stabilizing effect of 3-cyanopyridine Aeribacillus pallidus

Inhibitors

Inhibitors Comment Organism Structure
3-Cyanopyridine inhibition at concentrations greater than 0.2 M Aeribacillus pallidus
nicotinic acid inhibition at concentrations greater than 0.2 M Aeribacillus pallidus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-cyanopyridine + 2 H2O Aeribacillus pallidus
-
 nicotinic acid + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Aeribacillus pallidus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture best inducer of enzyme formation: benzonitrile Aeribacillus pallidus
-

Storage Stability

Storage Stability Organism
-80°C, 0.1 M potassium phosphate, pH 7.0, 5 mM EDTA, stored as packed cells, no loss of activity Aeribacillus pallidus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-cyanopyridine + 2 H2O
-
 Aeribacillus pallidus nicotinic acid + NH3
-
 ?

Synonyms

Synonyms Comment Organism
3-cyanopyridinase
-
 Aeribacillus pallidus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
60
-
-
 Aeribacillus pallidus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Aeribacillus pallidus