Any feedback?
Literature summary for 3.5.4.B9 extracted from
- Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein (2011), J. Biol. Chem., 286, 26568-26575.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of activation-induced deaminase, i.e. AID, and APOBEC3G in Escherichia coli strain BW310 and in human HEK293T cells | Mus musculus |
| expression of activation-induced deaminase, i.e. AID, and APOBEC3G in Escherichia coli strain BW310 and in human HEK293T cells | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E259Q | site-directed mutagenesis | Mus musculus |
| additional information | phospho-mimetic mutations inhibit DNA cytidine deaminase activity | Mus musculus |
| additional information | phospho-mimetic mutations inhibit DNA cytidine deaminase activity | Homo sapiens |
| T218A | site-directed mutagenesis | Mus musculus |
| T218E | site-directed mutagenesis | Mus musculus |
| T27A | site-directed mutagenesis | Mus musculus |
| T27E | site-directed mutagenesis | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein | Mus musculus |
| phosphoprotein | phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| activation-induced deaminase | - |
Mus musculus |
| activation-induced deaminase | - |
Homo sapiens |
| APOBEC3G | - |
Mus musculus |
| APOBEC3G | - |
Homo sapiens |
| DNA cytidine deaminase | - |
Mus musculus |
| DNA cytidine deaminase | - |
Homo sapiens |
| More | cf. EC 3.5.4.14 | Mus musculus |
| More | cf. EC 3.5.4.5 | Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | - |
assay at | Mus musculus |
| 7.6 | - |
assay at | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
