Application | Comment | Organism |
---|---|---|
diagnostics | serum tADA and ADA2 may serve as useful indicators for diagnosis of CGD, LADs, IgA deficiency, SCID, HIM and WAS patients as a supplementary laboratory test in combination with clinical, immunological, and other laboratory findings | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients with various primary immunodeficiency (PID) syndromes | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood serum | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
tADA and ADA2 levels are higher in patients with Chronic Granulomatous Disease (CGD), Leukocyte Adhesion Deficiency (LAD), hyper IgM (HIM) and Wiskott-Aldrich Syndrome (WAS) than those of corresponding controls. There is a significant elevation of tADA and ADA1 activities in IgA deficiency patients as compared to healthy individuals | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + H2O | - |
Homo sapiens | inosine + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADA | - |
Homo sapiens |
adenosine deaminase | - |
Homo sapiens |
TadA | - |
Homo sapiens |