Literature summary for 3.5.4.38 extracted from

Kuraoka, M.; Holl, T.M.; Liao, D.; Womble, M.; Cain, D.W.; Reynolds, A.E.; Kelsoe, G.
Activation-induced cytidine deaminase mediates central tolerance in B cells (2011), Proc. Natl. Acad. Sci. USA, 108, 11560-11565.

Search for more literature for 3.5.4.38

Cloned(Commentary)

Cloned (Comment)	Organism
expression of 3H9 VDJ knock-in alleles in genomic DNA of immature/T1, mature follicular B cells, and thymocytes from 3H9 and 3H9.Aicda-/- mice, quantitative expression analysis by PCR and immunofluorescence	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	generation of several enzyme-deficient Aicda-/- mice	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	gene Aicda	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
B-lymphocyte	AID expression occurs first in pro-B cells and increases on further development, peak AID expression is in immature and T1 B cells from bone marrow, is lower in splenic T1 B cells, and decreases precipitously in the splenic transitional 2 and mature B-cell compartments	Mus musculus	-
additional information	AID cDNA is undetectable in totipotent hematopoietic progenitors, and in cells committed to the T lymphocyte or myeloid lineages	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
activation-induced cytidine deaminase	-	Mus musculus
AICDA	-	Mus musculus

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Release 2023.1 (January 2023)