Literature summary for 3.5.4.37 extracted from

Lehmann, K.A.; Bass, B.L.
The importance of internal loops within RNA substrates of ADAR1 (1999), J. Mol. Biol., 291, 1-13.

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Organism

Organism	UniProt	Comment	Textmining
Xenopus laevis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
adenine in double-stranded RNA + H2O	dsRNA is deaminated at the same sites whether it exists as a free molecule or is flanked by internal loops. Internal loops delineate helix ends for ADAR1. Since ADAR1 deaminates short RNAs at fewer adenosines than long RNAs, loops decrease the number of deaminations within an RNA by dividing a long RNA into shorter substrates	Xenopus laevis	hypoxanthine in double-stranded RNA + NH3	-	?

Synonyms

Synonyms	Comment	Organism
ADAR1	-	Xenopus laevis

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Release 2023.1 (January 2023)